General Information

  • ID:  hor006921
  • Uniprot ID:  P09382??3-135)
  • Protein name:  Galectin-1
  • Gene name:  LHB
  • Organism:  Homo sapiens
  • Family:  NA
  • Source:  Human
  • Expression:  Expressed in placenta; maternal decidua and fetal membranes. Within placenta; expressed in trophoblasts; stromal cells; villous endothelium; syncytiotrophoblast apical membrane and villous stroma. Wit
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
  • GO MF:  GO:0062023 collagen-containing extracellular matrix; GO:0005737 cytoplasm; GO:0005829 cytosol; GO:0005788 endoplasmic reticulum lumen; GO:0070062 extracellular exosome; GO:0005576 extracellular region; GO:0005615 extracellular space; GO:1990724 galectin complex; GO:0005886 plasma membrane
  • GO BP:  GO:0003723 RNA binding; GO:0048018 receptor ligand activity; GO:0043236 laminin binding; GO:0030395 lactose binding
  • GO CC:  GO:0042981 regulation of apoptotic process; GO:0031295 T cell costimulation; GO:0098609 cell-cell adhesion; GO:0045445 myoblast differentiation; GO:2000329 negative regulation of T-helper 17 cell lineage commitment; GO:0002317 plasma cell differentiation; GO:0043065 positive regulation of apoptotic process; GO:0043123 positive regulation of canonical NF-kappaB signal transduction; GO:0050729 positive regulation of inflammatory response; GO:0006915 apoptotic process; GO:0046598 positive regulation of viral entry into host cell

Sequence Information

  • Sequence:  CGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  • Length:  133
  • Propeptide:  MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    NA

Physical Information

Mass: Formula:
Absent amino acids: Common amino acids:
pI: Basic residues:
Polar residues: Hydrophobic residues:
Hydrophobicity: Boman Index:
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index
Instability Index: Extinction Coefficient cystines:
Absorbance 280nm:

Literature

  • PubMed ID:  NA
  • Title:  NA